Banca de QUALIFICAÇÃO: ALINE DE ALMEIDA FERREIRA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : ALINE DE ALMEIDA FERREIRA
DATA : 10/03/2020
HORA: 14:00
LOCAL: sala S17, Térreo, Bloco Delta, Campus SBC da Fundação Universidade Federal do ABC, localizada na Alameda da Universidade, s/n, Bairro Anchieta - São Bernardo do Campo, SP.
TÍTULO:

Reconstruction and computational modelling of  inflammatory pathways activated by ketogenic diet through RNA-Seq dataset analysis.

PÁGINAS: 56
GRANDE ÁREA: Engenharias
ÁREA: Engenharia Biomédica
SUBÁREA: Bioengenharia
ESPECIALIDADE: Processamento de Sinais Biológicos
RESUMO:

Inflamation is a dinamic and complex process that aims the total tissuerecovery in face to microorganisms action, tissue gamage, trauma or othertypes of stress. Obesity is a inflammatory, chronic and sistemic processevidenced by increasing fat that predisposes to chronic diseases such as type2 diabetes, fatty liver and cancer, for example. To control obesity, manytypes of diet restrictions show good results, including caloric restrition andketogenic diet, moreover, evidences show that this diets improve longevityand oxidative aging damage from DNA in individuals under this diets.This project will investigate the gene expression under ketogenic dietsearching for differentially expressed genes and biologycal networks relatedto inflammation and DNA repair.So far three publically available microarray datasets of mouse liver havebeen analysed and reported differentially expressed genes and Gene Ontologycategories that are statistically overrepresented. Three RNA-Seq datasets areunder analysis and are target for differentially expressed genes analysis andGene Ontology categories enrichment analysis.The final scope of the project is to integrate the six analyses to adresswhich genes and biological networks respond to ketogenic diet.

MEMBROS DA BANCA:
Presidente - Interno ao Programa - 2125782 - ANDREA CECILIA DORION RODAS
Membro Titular - Examinador(a) Externo ao Programa - 1722875 - DAVID CORREA MARTINS JUNIOR
Membro Titular - Examinador(a) Externo ao Programa - 1912347 - NATHALIA DE SETTA COSTA
Membro Suplente - Examinador(a) Interno ao Programa - 2090031 - ILKA TIEMY KATO PRATES
Membro Suplente - Examinador(a) Externo ao Programa - 1672728 - ANA CAROLINA SANTOS DE SOUZA GALVAO
Membro Suplente - Examinador(a) Externo ao Programa - 3066269 - VINICIUS DE ANDRADE OLIVEIRA