Banca de QUALIFICAÇÃO: THIAGO KENZO FUJIOKA SHIDA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : THIAGO KENZO FUJIOKA SHIDA
DATA : 05/11/2021
HORA: 18:00
LOCAL: online
TÍTULO:

Effect of freezing of gait and antiparkinsonian medication on the gait in individuals with Parkinson's disease

PÁGINAS: 31
GRANDE ÁREA: Engenharias
ÁREA: Engenharia Biomédica
SUBÁREA: Bioengenharia
ESPECIALIDADE: Modelagem de Sistemas Biológicos
RESUMO:

Individuals with Parkinson's disease (PD) present changes in gait due to complications of the pathology, such as greater muscle rigidity, bradykinesia, less automaticity of movements, and postural balance problems. The standard gold treatment for PD is pharmacological therapy with dopaminergic medication, which improves motor and non-motor issues of the disease. Studies report the effects of dopaminergic medication on spatiotemporal gait parameters, but few studies have evaluated the effects on kinematic and kinetic parameters. A factor that changes the gait parameters of these individuals is the presence of freezing of gait (FoG). However, the interaction between FoG and antiparkinsonian medication on PD gait is not documented. Thus, this study aims to evaluate the effects of antiparkinsonian medication and the presence of freezing of gait on the kinematic and kinetic parameters of gait in individuals with PD. Twenty-two individuals with a clinical diagnosis of idiopathic PD (17 men and 5 women; mean age = 64.1 years, SD = 10.5; mean height = 166.8 cm, SD = 7.1; mean weight = 71.4) participated in this study kg, SD = 12.3), being 11 with freezing of gait (FoG +) and 11 without freezing of gait (FoG-). Participants with PD were evaluated in the ON and OFF medication periods. For the control group, 18 age-matched participants were selected from an open database. All participants walked on the floor on a 10-meter-long walkway at a comfortable, self-selected speed. The kinematic and kinetic variables of gait and the clinical characteristics of the groups in each condition will be compared in the following analyses: Group PD FoG+ and PD FoG- both in the ON condition and elderly group; Group PD FoG+ and PD FoG- both in the OFF condition and elderly group; Group (PD FoG+ and PD FoG-) and condition (ON and OFF). Linear mixed-effects models will be fitted, controlling for differences between demographic characteristics and clinical scales groups. The level of significance for all analyzes will be set at p < 0.05, and for analysis of interactions, the post hoc of Bonferroni will be used. Analyzes will be performed with the R program.

MEMBROS DA BANCA:
Presidente - Interno ao Programa - 2090962 - REGINALDO KISHO FUKUCHI
Membro Titular - Examinador(a) Externo ao Programa - 1957691 - RONNY CALIXTO CARBONARI
Membro Titular - Examinador(a) Externo à Instituição - ANDREA CRISTINA DE LIMA
Membro Suplente - Examinador(a) Interno ao Programa - 2352005 - RENATO NAVILLE WATANABE
Membro Suplente - Examinador(a) Externo à Instituição - LUIS MOCHIZUKI