Due to the diversity, heterogeneity and complexity of existing Health Information Systems, as well as the progress of population aging, the increase in chronic diseases and the emergence of public health emergencies, interoperability and the development of technological solutions dedicated to digital health is a challenge. complex process, but of great value to the population. Therefore, the main objective of the present work was to propose a systemic arrangement of digital health, representing health in the context of a superintelligent society. Based on exploratory research, of an applied nature and with a qualitative approach, this study began with an integrative review through the application of the Systematic Research Flow to understand the current situation of digitization in health and subsequently a bibliometric analysis was carried out to understanding the state of the art. Based on the built vision, a software architecture was proposed from a multilevel approach that provided for the application of digital technologies in a harmonious way to the attributes of the digital society, using the ISO/IEC/IEEE 42010:2011 standard and structuring based on Information and Communication Technologies in Health. Among the results, it was observed that digital health is a contemporary theme and presents a high growth within the literature. In addition, an increase in virtualization in healthcare environments has been reported in order to ensure personalization of healthcare services to patients. However, the interoperability between the different Health Information Systems stood out as a major challenge. Through the built architecture, a pattern was created that allows greater flexibility, interoperability and communication of the new Information and Communication Technologies in Health with the Health Information Systems in a context where the patient becomes the center and focus is the optimization of your well-being and quality of life. This study aimed to contribute to the literature, as it is a contemporary theme in the international and national literature, in addition to serving as a management tool for the digital transformation of patient-oriented Health Information Systems.