Banca de QUALIFICAÇÃO: JULIAN MATEO RAYO ALAPE

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : JULIAN MATEO RAYO ALAPE
DATA : 25/07/2022
HORA: 14:00
LOCAL: https://conferenciaweb.rnp.br/webconf/herculano
TÍTULO:

VIBRATIONAL CALCULATIONS AND SERS-ACTIVITY PREVISION OF HORMONE HEPCIDIN

PÁGINAS: 100
GRANDE ÁREA: Ciências Exatas e da Terra
ÁREA: Física
SUBÁREA: Física da Matéria Condensada
ESPECIALIDADE: Prop. Óticas e Espectrosc. da Mat. Condens; Outras Inter. da Mat. com Rad. e Part.
RESUMO:

The search for fast, accessible and inexpensive way to mass-testing SARS-Cov-2 infectiouS disease COVID-19 is an essential task. The actual gold-standard for COVID-19 screening is RT- PCR. However its high false-negative rate (∝ 29%) and poor sensitivity (∝ 71%) limits the action of medical care units in special in high-morbidity cases. Since it demands complex preparing and lab-site measurements in samples it is not a point-of-care method of test. Thus, new diagnostic methods need the tailored in order to overcome the RT-PCT limitations. Evidences had been presented relating COVID-19 mortality might to viral driven hyperinflammation. In this way iron-based dosages metabolite dosages had been recommended to probe the fatality rate. The detection of hepcidin hormone available in saliva is an option to be considered and the Surface Enhanced Raman Spectroscopy (SERS) technique is an interesting possibility to address this problem. The SERS has great potential for point-of-care applications in diagnosis and screening in biofluids like saliva. Thus the present project aims calculate the Raman-active vibrational modes and electrostatic potential mesh (MEP) of hepcidin biomolecule using Density Functional (DFT) calculations and the corresponding SERS activity over Au and Boehmite Surfaces.

MEMBROS DA BANCA:
Presidente - Interno ao Programa - 2218228 - LUANA SUCUPIRA PEDROZA
Membro Titular - Examinador(a) Interno ao Programa - 1309493 - PEDRO ALVES DA SILVA AUTRETO
Membro Titular - Examinador(a) Externo ao Programa - 1654772 - CAMILO ANDREA ANGELUCCI
Membro Suplente - Examinador(a) Interno ao Programa - 1760410 - JEVERSON TEODORO ARANTES JUNIOR
Membro Suplente - Examinador(a) Interno ao Programa - 1544408 - GUSTAVO MARTINI DALPIAN
Membro Suplente - Examinador(a) Externo ao Programa - 1760474 - PATRICIA APARECIDA DA ANA