Banca de DEFESA: BRUNA SANTOS SOUZA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : BRUNA SANTOS SOUZA
DATA : 17/03/2020
HORA: 14:30
LOCAL: Auditório, 8º andar, Bloco B, Campus SA da Fundação Universidade Federal do ABC, localizada na Avenida dos Estados, 5001, Santa Terezinha, Santo André, SP
TÍTULO:

Synthesis, evaluation of luminescent properties, and applications of organochalcogen-functionalized fluorophores.

PÁGINAS: 95
GRANDE ÁREA: Ciências Exatas e da Terra
ÁREA: Química
SUBÁREA: Química Orgânica
ESPECIALIDADE: Síntese Orgânica
RESUMO:

Aiming to synthesize Selenium and tellurium fluorescent organic compounds capable of acting as “on/off” devices by photoinduced electron transfer (PET) and which also have biological activity, the following starting materials were prepared:  diphenyl dichalcogenides, 4- (phenylchalcogenyl) -benzaldehydes, 4- (phenylchalcogenyl) -benzylamines, with an attempt to produce 3- (phenylchalcogenyl) –propylamines. These derivatives constitute a collection with six compounds that were characterized by 1H, 13C NMR, and high-resolution mass spectrometry. With this, different protocols were explored in an attempt to conjugate these compounds to the fluorophores 4-amino-7-methyl-coumarin, 1-aminomethyl-pyrene, 5-fluorescein isothiocyanate, and rhodamine B isothiocyanate. Among these, only the conjugation of 1 -aminomethyl-pyrene was successful for both chalcogens. The same characterization approach was also applied to a series of benzazoles comprised of benzimidazoles and benzothiazoles which had their partial photophysical characterization carried out together with the 1-aminomethyl-pyrene compounds. The absorption, emission, and excitation spectra were obtained for the nine compounds, and it was not possible to get quantum yields and lifetime due to limitations present in the equipment available. Finally, using dimethylsulfoxide (DMSO) and / or water as solvents, tests for adding dithiothreitol (DTT), hydrogen peroxide, L-Cysteine, hydrochloric acid and sodium hydroxide solutions were performed in order to observe the behavior of the emission intensity during oxidation and reduction of the aforementioned compounds.

MEMBROS DA BANCA:
Presidente - Interno ao Programa - 1623562 - RODRIGO LUIZ OLIVEIRA RODRIGUES CUNHA
Membro Titular - Examinador(a) Externo ao Programa - 1982740 - GUSTAVO MORARI DO NASCIMENTO
Membro Titular - Examinador(a) Externo à Instituição - TIMOTHY JOHN BROCKSOM - UFSCAR
Membro Suplente - Examinador(a) Interno ao Programa - 1766090 - MIRELA INES DE SAIRRE
Membro Suplente - Examinador(a) Externo à Instituição - DIOGO DE OLIVEIRA SILVA - UNIFESP