Banca de DEFESA: INGRID FERNANDES FREITTER

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : INGRID FERNANDES FREITTER
DATE: 08/05/2023
TIME: 08:30
LOCAL: Remoto
TITLE:

Study of the expression of scFv anti-KLK3 antibodies in bacteria

PAGES: 100
BIG AREA: Ciências Biológicas
AREA: Bioquímica
SUMMARY:

The development of biopharmaceuticals gained notoriety with the use of recombinant DNA, revolutionizing the process of biopharmaceuticals, having several advantages such as the reduction of side effects in patients. KLK3 is a proteolytic enzyme belonging to the group of 15 enzymes called KLK1-15 related to body homeostasis and various diseases. Also known as PSA, KLK3 is related to prostate cancer, where its serum level is increased, with this, it is possible to use this enzyme as a biomarker of prostate cancer. The present work tests a selection of bivalent antibody fragments of the scFv-Fc type against the KLK3 enzyme in prokaryotic cells, which may be used, in the future, for the detection of PSA.

COMMITTEE MEMBERS:
Presidente - Interno ao Programa - 1696841 - LUCIANO PUZER
Membro Titular - Examinador(a) Interno ao Programa - 2605490 - SERGIO DAISHI SASAKI
Membro Titular - Examinador(a) Externo à Instituição - JOCÉLIA PEREIRA DE CARVALHO OLIVEIRA
Membro Suplente - Examinador(a) Interno ao Programa - 003.058.336-50 - RENATO FERREIRA DE FREITAS - USP
Membro Suplente - Examinador(a) Externo à Instituição - MARCELO BERGAMIN ZANI