Analysis of electrophysiological recordings during temporal learning
Time is a fundamental feature of the physical world and an prominent component of animal behavior. However, the neurobiological underpinnings of interval timing capability have yet to be fully undestood. Two regions are often implicated as central to this ability: the prefrontal cortex (PFC) and the striatum (STR). However, recent experimental results from the research group point to a dissociation between these two systems throughout learning, with greater PFC engagement during acquisition, but not in the expression of temporal behavior, and the opposite for the striatum. This work proposes an exploratory analysis of electrophysiological data resulting from these experiments using three metrics: an index of sequentiality of action potential firings, an index of resizing of this spike activity, and the estimation of the coupling between frequencies of local field potentials . Results obtained in the analysis of the first metric suggest that the difference in sequentiality between these two regions, observed in other works and which may be a mechanism for this timing, also exists in this data set, despite the differences between the two experimental designs.