Cognitive processes characterization and neural correlates of reading in cognitively healthy elderly: a fNIRS and eyetracking study
Reading and comprehension skills are essential in daily life. In healthy aging, if part of the crystallized knowledge remains intact other cognitive functions directly related to the good performance in these skills are declining. In addition, it is under-discussed how strategy changes are applied by this population to achieve better performance or to compensate for the cognitive decline associated with age. There is a need for studies that better characterize the processes of reading and understanding in neurotypical elderly people, as well as to evaluate neuroscience tools as a potential complement for this characterization. For this purpose, the present study carried out two experiments with 40 elderly participants. The first evaluated the neural processes and correlates involved in reading words based on the double-route model (Coltheart et al., 2001), using the functional near-infrared spectroscopy technique (fNIRS). We analyzed the hemodynamic signal of oxy and deoxyhemoglobin and compared task conditions versus resting in the frontal, temporal and inferior parietal cortex, bilaterally. We observed a lexicality and regularity effect in reading fluency, dorsal path recruitment for the pseudoword condition and recruitment of the regions considered semantic hubs for irregular words. The bilateral cortical activation and without significant differences between the hemispheres support the HAROLD model of neuronal compensation in the elderly population, proposed by Cabeza in 2002. The second experiment evaluated the performance in the read and heard phrases comprehension concomitant to the search strategy evaluation using eye-tracking. We observed that the elderly had greater difficulty in grammatically more complex blocks, associated with a greater demand for information processing. In addition, the strategy observed was a search with greater engagement in the regions of interest located in the upper left and right quadrants, with greater fixation in the target region.