BIOLOGICAL ACTIVITY PRODUCED BY BACTERIA ISOLATED FROM MARINE SPONGES ON THE COAST OF SÃO PAULO.
Marine sponges are invertebrate animals that have a wide distribution and, therefore, occupy several oceanic regions. Currently, these are also considered holobionts and, therefore, several researches have been developed with a focus on the complexity of the host, the symbionts and their relationships with each other. Furthermore, culture-dependent and culture-independent studies have provided access to symbiont genes and the putative functions they play for host sponges. Thus, this project gathers and discusses the results about the representativeness and bacterial diversity, isolated from the sponges Aplysina fulva and Aplysina caissara, collected on the coast of the São Paulo State, the last species being endemic; presents the isolates that amplified the genes of interest Polypeptide synthases types I and II (PKS I and PKS II) and Non-ribosomal peptide synthetases (NRPS), known to be involved in the production of secondary metabolites, as well as showing the biological and cytotoxic activity of isolated, thus denoting the promising investigation of natural compounds of biotechnological interest.